Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | DDO | Q99489 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367711 | 0.84 | DAO (0.61) | BRD4PDGFRBPDGFRADAODDO | |
| SCHEMBL31065665 | 0.81 | BRD4 (0.58) | RXFP1BRD4MEN1KMT2APDGFRB | |
| SCHEMBL5716749 | 0.80 | PDGFRB (0.72) | MEN1KMT2APDGFRBPDGFRADAO | |
| SCHEMBL16627895 | 0.78 | MEN1 (0.58) | RXFP1BRD4MEN1KMT2APDGFRB | |
| SCHEMBL29505966 | 0.78 | DAO (0.58) | BRD4MEN1KMT2ADAODDO | |
| SCHEMBL5464080 | 0.78 | DAO (0.58) | BRD4MEN1KMT2ADAODDO | |
| SCHEMBL19414710 | 0.77 | SMYD3 (0.58) | BRD4DAODDOSMYD3KDM4E | |
| SCHEMBL1366351 | 0.76 | DAO (0.65) | RXFP1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL34468782 | 0.76 | KDM4E (0.58) | RXFP1BRD4MEN1KMT2ASMYD3 | |
| SCHEMBL29364659 | 0.76 | KDM4E (0.59) | BRD4MEN1KMT2ADAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710223-B | Preparation method of 3-aryl quinolinone derivative | 广东工业大学 | 2024-05-10 | — | — | CN | disclosed |