SCHEMBL31065665

SCHEMBL31065665

Cc1ccccc1C(=O)c1cc2ccccc2[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.58
DAO P14920 1/20 0.50
DDO Q99489 1/20 0.50
SMYD3 Q9H7B4 2/20 0.49
PADI4 Q9UM07 2/20 0.48
FLT3 P36888 1/20 0.47
KDM4E B2RXH2 4/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPK10 P53779 1/20 0.45
IL4I1 Q96RQ9 1/20 0.44
CHEK1 O14757 1/20 0.44
KDR P35968 1/20 0.44
SPR P35270 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1367711 0.89 DAO (0.61) BRD4DAODDOSMYD3PADI4
SCHEMBL29206331 0.81 RXFP1 (0.57) BRD4DAODDOSMYD3PADI4
SCHEMBL5464080 0.79 DAO (0.58) BRD4DAODDOSMYD3PADI4
SCHEMBL29505966 0.79 DAO (0.58) BRD4DAODDOSMYD3PADI4
SCHEMBL31394 0.77 KDM4E (0.59) BRD4DAODDOSMYD3PADI4
SCHEMBL29364659 0.77 KDM4E (0.59) BRD4DAODDOSMYD3PADI4
SCHEMBL29390425 0.76 DAO (0.58) BRD4DAODDOSMYD3PADI4
Fluoride SCHEMBL29664116 0.76 KDM4E (0.58) BRD4DAODDOSMYD3PADI4
Hydrochloric Acid SCHEMBL5027809 0.76 KDM4E (0.58) BRD4DAODDOSMYD3PADI4
SCHEMBL16627746 0.76 DAO (0.58) BRD4DAODDOSMYD3PADI4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561750-A Synthesis method and application of 2-methylbenzoyl quinolinone 西北农林科技大学 2024-08-30 CN claimed
CN-118561750-A Synthesis method and application of 2-methylbenzoyl quinolinone 西北农林科技大学 2024-08-30 CN disclosed
CN-118561750-A Synthesis method and application of 2-methylbenzoyl quinolinone 西北农林科技大学 2024-08-30 CN disclosed
CN-118561750-A Synthesis method and application of 2-methylbenzoyl quinolinone 西北农林科技大学 2024-08-30 CN disclosed