Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206349 | 1.00 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL11588542 | 0.85 | POLB (0.62) | MEN1KMT2APOLBMAPTHPGD | |
| SCHEMBL6717026 | 0.84 | MEN1 (0.57) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL29521360 | 0.82 | POLB (0.68) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL19954280 | 0.82 | POLB (0.68) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL8337821 | 0.81 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL6717493 | 0.81 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL28002396 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL11763994 | 0.78 | KMT2A (0.59) | MEN1KMT2ANPC1RAB9AMITF | |
| SCHEMBL700858 | 0.78 | KMT2A (0.59) | MEN1KMT2ANPC1RAB9AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539084-B | Preparation method of mirabegron and intermediate thereof | 威智医药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |