Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387120 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL29770615 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL5397803 | 0.79 | KDM4E (0.39) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL15577470 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL27238766 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL1750877 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL1853597 | 0.77 | TDP1 (0.52) | ALDH1A1CYP1A2CYP2C19TDP1LMNA | |
| SCHEMBL611871 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CYP2C19TDP1 | |
| SCHEMBL16465686 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C19TDP1 | |
| SCHEMBL17773615 | 0.74 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C19TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |