Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849370 | 1.00 | FNTA (0.33) | FNTAFNTBCYP11B1CYP11B2HSD17B1 | |
| SCHEMBL30849369 | 1.00 | FNTA (0.33) | FNTAFNTBCYP11B1CYP11B2HSD17B1 | |
| SCHEMBL16043515 | 0.76 | DYRK1A (0.35) | FNTAFNTBKMT2A | |
| SCHEMBL568921 | 0.76 | PTGS1 (0.39) | FNTAFNTBALDH1A1KMT2A | |
| SCHEMBL1915232 | 0.76 | KMT2A (0.41) | FNTAFNTBKMT2A | |
| SCHEMBL14416135 | 0.74 | CES1 (0.52) | CYP11B2ALDH1A1GAAKMT2A | |
| SCHEMBL15070844 | 0.73 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL28678769 | 0.72 | ALDH1A1 (0.47) | CYP11B1CYP11B2ALDH1A1GAAKMT2A | |
| SCHEMBL20414234 | 0.72 | MEN1 (0.38) | CYP11B2ALDH1A1GAAKMT2A | |
| SCHEMBL29362495 | 0.72 | ALDH1A1 (0.47) | CYP11B1CYP11B2ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800949-A | Pyrimidine-containing polycyclic derivative, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-02 | — | — | CN | disclosed |