Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143147 | 0.79 | SLC6A1 (0.43) | USP2TSHRSLC6A9CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL26962043 | 0.78 | SLC6A1 (0.43) | USP2TSHRSLC6A9CYP2C19CYP3A4 | |
| SCHEMBL10163092 | 0.76 | USP2 (0.50) | USP2NPSR1TSHRSLC6A9CYP2C19 | |
| SCHEMBL10163087 | 0.76 | USP2 (0.50) | USP2NPSR1TSHRSLC6A9CYP2C19 | |
| SCHEMBL1582491 | 0.76 | — | — | |
| SCHEMBL12581653 | 0.76 | NPSR1 (0.50) | NPSR1TSHRCYP3A4LMNAALDH1A1 | |
| SCHEMBL15939388 | 0.74 | NPSR1 (0.48) | NPSR1TSHRCYP3A4LMNAALDH1A1 | |
| SCHEMBL1441490 | 0.73 | USP30 (0.46) | USP2CYP2C9CYP2D6ALDH1A1CYP1A2 | |
| SCHEMBL21230450 | 0.72 | USP2 (0.34) | USP2TSHRCYP2C19CYP3A4CYP1A2 | |
| SCHEMBL22125252 | 0.71 | USP2 (0.35) | USP2NPSR1TSHRCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596551-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | Trasveda Ltd. (KY) | 2025-08-06 | — | — | EP | disclosed |
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |