Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322060 | 0.89 | MAPT (0.40) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL26922015 | 0.81 | GAA (0.41) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL31569422 | 0.81 | MAPT (0.43) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL2320088 | 0.81 | MAPT (0.43) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL30946511 | 0.77 | MAPT (0.40) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL19000145 | 0.77 | GAA (0.40) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL9725076 | 0.76 | MAPT (0.42) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL21684641 | 0.76 | MAPT (0.44) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL8112444 | 0.74 | ALDH1A1 (0.40) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL5488909 | 0.74 | ALDH1A1 (0.40) | MAPTGAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596551-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | Trasveda Ltd. (KY) | 2025-08-06 | — | — | EP | disclosed |
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |