Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066265 | 1.00 | GPR119 (0.52) | GPR119IDO1TDO2FPR2CNR1 | |
| SCHEMBL1704960 | 0.86 | GPR119 (0.51) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL21877150 | 0.84 | GPR119 (0.56) | GPR119FPR2CNR1TGFBR1ALDH1A1 | |
| SCHEMBL5656992 | 0.82 | CKS1B (0.48) | GPR119ALDH1A1LMNAMAPT | |
| SCHEMBL20294520 | 0.80 | GPR119 (0.56) | GPR119FPR2CNR1TGFBR1ALDH1A1 | |
| SCHEMBL29207812 | 0.79 | DDB1 (0.49) | GPR119 | |
| SCHEMBL30066499 | 0.79 | DDB1 (0.49) | GPR119 | |
| SCHEMBL24671756 | 0.79 | GPR119 (0.74) | GPR119CNR1 | |
| SCHEMBL29990508 | 0.79 | GPR119 (0.74) | GPR119CNR1 | |
| SCHEMBL24671505 | 0.79 | GPR119 (0.52) | GPR119IDO1TDO2FPR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |