Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832009 | 0.95 | ALDH1A1 (0.39) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208009 | 0.85 | HTR2A (0.38) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208042 | 0.85 | HTR2A (0.38) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208076 | 0.85 | HTR2A (0.39) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29207960 | 0.85 | HRH3 (0.39) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208068 | 0.83 | HTR2A (0.47) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29207970 | 0.83 | ALDH1A1 (0.43) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29207925 | 0.82 | KDM4E (0.43) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208022 | 0.82 | MAPK14 (0.39) | HTR2AHTR2CKCNH2HTR1ATMEM97 | |
| Trifluoroacetic Acid SCHEMBL29208069 | 0.81 | ALDH1A1 (0.39) | HTR2AHTR2CKCNH2HTR1ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |