Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831994 | 0.95 | KMT2A (0.42) | HTR2AHTR2CKCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL29207962 | 0.90 | HTR2A (0.38) | CHRM4HTR2AHTR2CKCNH2KMT2A | |
| Trifluoroacetic Acid SCHEMBL29208051 | 0.87 | HTR2A (0.42) | CHRM4HTR2AHTR2CKCNH2KMT2A | |
| Trifluoroacetic Acid SCHEMBL29208031 | 0.86 | GSK3B (0.38) | HTR2AHTR2CKCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL29207973 | 0.86 | HTR2A (0.40) | HTR2AHTR2CKCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL29207934 | 0.85 | KMT2A (0.45) | CHRM4HTR2AHTR2CKCNH2KMT2A | |
| Trifluoroacetic Acid SCHEMBL29208053 | 0.85 | PTGIR (0.41) | HTR2AHTR2CKCNH2KMT2AMEN1 | |
| SCHEMBL30842029 | 0.84 | HTR4 (0.39) | HTR2AHTR2CKCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL29207949 | 0.84 | SMN1; SMN2 (0.41) | HTR2AHTR2CKCNH2 | |
| Trifluoroacetic Acid SCHEMBL29207974 | 0.82 | HTR2A (0.48) | CHRM4HTR2AHTR2CKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |