Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TK2 | O00142 | 5/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NT5C | Q8TCD5 | 1/20 | 0.38 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920229 | 1.00 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2920850 | 1.00 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2920226 | 1.00 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2920233 | 1.00 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2920223 | 1.00 | TK1 (0.53) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2915114 | 0.91 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2915121 | 0.91 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2915125 | 0.91 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2919241 | 0.91 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL2919240 | 0.91 | TK1 (0.64) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204415-B1 | 5-(E)-BROMOVINYL URACIL ANALOGUES AND RELATED PYRIMIDINE NUCLEOSIDES AS ANTI-VIRAL AGENTS AND METHODS OF USE | UNIV YALE (US) | 2010-09-08 | — | — | EP | disclosed |
| US-6653318-B1 | Varicella zoster and epstein barr viruses | YALE UNIVERSITY | 2003-11-25 | — | — | US | disclosed |