Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208735 | 0.88 | TIPARP (0.44) | TRPV1PPARGPPARDPPARARIPK1 | |
| SCHEMBL21868477 | 0.84 | RIPK1 (0.52) | TRPV1RIPK1RORCKDM4EPARP1 | |
| SCHEMBL29208728 | 0.83 | MAPT (0.53) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL30776184 | 0.83 | MAPT (0.53) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL29208793 | 0.81 | TRPV1 (0.40) | TRPV1RIPK1RORCTIPARPCHRM1 | |
| SCHEMBL26124820 | 0.80 | PPARG (0.41) | TRPV1PPARGPPARDPPARANPC1 | |
| SCHEMBL26127908 | 0.80 | PPARG (0.39) | TRPV1PPARGPPARDPPARANPC1 | |
| SCHEMBL3815501 | 0.79 | TRPV1 (0.54) | TRPV1RORCALDH1A1KDM4EMAPT | |
| SCHEMBL29208849 | 0.79 | TRPV1 (0.39) | TRPV1RIPK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29208763 | 0.79 | RIPK1 (0.42) | TRPV1RIPK1CHRM2CHRM1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777099-A | PARP7 inhibitors and uses thereof | 诺沃斯达药业(上海)有限公司 | 2024-03-29 | — | — | CN | disclosed |