Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PAK4 | O96013 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.46 |
| ▸ | CDK7 | P50613 | 2/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | MELK | Q14680 | 2/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25303779 | 0.89 | EGFR (0.58) | ALKEGFRBTKINSRIGF1R | |
| SCHEMBL29208829 | 0.87 | ALK (0.61) | ALKINSR | |
| SCHEMBL29208841 | 0.86 | EGFR (0.54) | ULK1ALKEGFRBTKCDK19 | |
| SCHEMBL25296774 | 0.84 | MAP4K1 (0.51) | ALKEGFRBTKMAP4K1CDK19 | |
| SCHEMBL29208869 | 0.83 | EGFR (0.44) | EGFRBTKMAP4K1 | |
| SCHEMBL25001766 | 0.83 | ULK1 (0.70) | ULK1ALKEGFRPTK2MET | |
| SCHEMBL29208821 | 0.83 | EGFR (0.47) | ALKEGFRBTK | |
| SCHEMBL29208809 | 0.82 | EGFR (0.53) | EGFR | |
| SCHEMBL25296645 | 0.80 | EGFR (0.41) | ALKEGFRBTKINSRMAP4K1 | |
| SCHEMBL29208831 | 0.77 | EGFR (0.53) | ALKEGFRPTK2BTKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |