SCHEMBL29209032

SCHEMBL29209032

Cc1cc(N2CCCCC2)c(N)c(C)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.49
GAA P10253 4/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 3/20 0.49
KMT2A Q03164 3/20 0.49
THRB P10828 2/20 0.49
NR4A1 P22736 1/20 0.49
PTK2B Q14289 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.43
HTT P42858 3/20 0.42
S100B P04271 2/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PKM P14618 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KEAP1 Q14145 1/20 0.41
ALDH1A3 P47895 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL531525 0.77 ALDH1A1 (0.41) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL533566 0.77 ALDH1A1 (0.53) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL532945 0.74 ALDH1A1 (0.42) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL533139 0.74 ALDH1A1 (0.55) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL11148223 0.74 ALDH1A1 (0.48) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL14962281 0.74 ALDH1A1 (0.47) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL10810138 0.74 ALDH1A1 (0.47) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL8324237 0.74 ALDH1A1 (0.53) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL11439640 0.72 ALDH1A1 (0.56) ALDH1A1GAAMEN1MAPTKMT2A
SCHEMBL19700141 0.71 ALDH1A1 (0.48) ALDH1A1GAAMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999259-A Iron death modulators, their preparation and use 维泰瑞隆有限公司 2024-05-07 CN disclosed