Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29209123 | 0.77 | MAPT (0.47) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL24306740 | 0.74 | MAPT (0.42) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL28870981 | 0.73 | POLB (0.43) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL1450379 | 0.73 | BRD4 (0.51) | MAPTPOLBHSD17B10PARP1ALOX5 | |
| SCHEMBL18128201 | 0.70 | POLB (0.49) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL26771562 | 0.70 | POLB (0.40) | MAPTPOLBHSD17B10PARP1ALDH1A1 | |
| SCHEMBL13901417 | 0.69 | POLB (0.48) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL16163265 | 0.68 | ALOX5 (0.43) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL15492720 | 0.68 | BRD4 (0.45) | MAPTPOLBHSD17B10PARP1ALPL | |
| SCHEMBL29209006 | 0.68 | NISCH (0.47) | MAPTALPLMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |