Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367193 | 0.80 | TAAR1 (0.54) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL29018028 | 0.76 | CYP1A2 (0.50) | TAAR1MAOBIDO1AGXTMAOA | |
| SCHEMBL5795896 | 0.76 | IDO1 (0.60) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL17070611 | 0.76 | TAAR1 (0.50) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL15079869 | 0.76 | MAOB (0.58) | TAAR1MAOBMAOA | |
| SCHEMBL4579423 | 0.76 | TAAR1 (0.50) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL7437052 | 0.76 | TAAR1 (0.68) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL660826 | 0.75 | TDP1 (0.52) | TAAR1MAOBIDO1LOXL2MAOA | |
| SCHEMBL23183196 | 0.73 | TAAR1 (0.46) | TAAR1MAOBIDO1AGXTLOXL2 | |
| SCHEMBL6542140 | 0.73 | TAAR1 (0.46) | TAAR1MAOBIDO1AGXTLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073353-B | Lignan derivative, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-05-14 | — | — | CN | disclosed |