SCHEMBL5795896

SCHEMBL5795896

NOCCc1ccc(F)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.60
AGXT P21549 3/20 0.60
TAAR1 Q96RJ0 3/20 0.56
MAOB P27338 4/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
AOC3 Q16853 2/20 0.47
AOC2 O75106 1/20 0.41
MAOA P21397 1/20 0.41
ELOVL1 Q9BW60 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5798706 0.86 IDO1 (0.63) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL8973679 0.85 IDO1 (0.55) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL14349913 0.78 GFER (0.62) IDO1MAOBLOXL2MAOA
SCHEMBL17070611 0.76 TAAR1 (0.50) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL15079869 0.76 MAOB (0.58) TAAR1MAOBMAOA
SCHEMBL4579423 0.76 TAAR1 (0.50) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL7437052 0.76 TAAR1 (0.68) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL8097545 0.76 TAAR1 (0.61) IDO1AGXTTAAR1MAOBLOXL2
SCHEMBL6264538 0.76 IDO1 (0.64) IDO1AGXTTAAR1MAOB
SCHEMBL538855 0.75 IDO1 (0.74) IDO1AGXTTAAR1MAOBLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006037496-A1 POLYHALOGENATED PROPENE BENZOQUINONE DIOXIME DERIVATIVES AND ITS USE AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2006-04-13 WO disclosed
WO-2005095330-A1 NOVEL DICHLOROPROPENE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2005-10-13 WO disclosed