Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298254 | 0.84 | TSHR (0.68) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL9462068 | 0.81 | TSHR (0.84) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL11509921 | 0.79 | TSHR (0.62) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL27380746 | 0.79 | TSHR (0.62) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL16048460 | 0.79 | TSHR (0.62) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL42755 | 0.79 | — | — | |
| SCHEMBL4675666 | 0.77 | TSHR (0.67) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL10010574 | 0.77 | TSHR (0.67) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL5314281 | 0.77 | TSHR (0.60) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL1373745 | 0.77 | TSHR (0.67) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | disclosed |