Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3899899 | 0.99 | FGFR1 (0.40) | FGFR1KMT2AMEN1MAPTALOX15 | |
| SCHEMBL2928661 | 0.89 | KMT2A (0.38) | KMT2AMEN1MAPTALOX15HSD17B10 | |
| SCHEMBL5449603 | 0.89 | MEN1 (0.49) | KMT2AMEN1MAPTALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL5894517 | 0.89 | KMT2A (0.38) | KMT2AMEN1MAPTALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL2927668 | 0.88 | MEN1 (0.48) | KMT2AMEN1MAPTALOX15HSD17B10 | |
| SCHEMBL6503870 | 0.88 | FGFR1 (0.45) | FGFR1KMT2AMEN1AURKAFLT3 | |
| SCHEMBL2922698 | 0.88 | KMT2A (0.47) | FGFR1KMT2AMEN1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL2927706 | 0.88 | FGFR1 (0.44) | FGFR1KMT2AMEN1AURKAFLT3 | |
| SCHEMBL3903873 | 0.87 | FGFR1 (0.42) | FGFR1KMT2AMEN1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL2929385 | 0.86 | KMT2A (0.38) | FGFR1KMT2AMEN1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231643-A1 | AMIDOMETHYL-SUBSTITUTED OXINDOLE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF VASOPRESSIN-DEPENDENT ILLNESSES | Abbott GmbH & Co. KG (DE) | 2010-09-29 | — | — | EP | disclosed |
| EP-1644376-B1 | PYRROLO 3,4-c PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009071687-A1 | AMIDOMETHYL-SUBSTITUTED OXINDOLE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF VASOPRESSIN-DEPENDENT ILLNESSES | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |