SCHEMBL29210657 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	NR1H2	P55055	2/20	0.41

▸	ESR2	Q92731	1/20	0.39

▸	NPC1	O15118	2/20	0.37

▸	DRD2	P14416	3/20	0.37

▸	UCHL1	P09936	1/20	0.37

▸	RAB9A	P51151	1/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	GPR119	Q8TDV5	1/20	0.35

▸	USP30	Q70CQ3	1/20	0.35

▸	KDM1A	O60341	1/20	0.34

▸	RORC	P51449	2/20	0.34

▸	HSD11B1	P28845	1/20	0.34

▸	SETD7	Q8WTS6	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30983671	1.00	NR1H2 (0.41)	NR1H2ESR2NPC1DRD2UCHL1
SCHEMBL30983727	0.88	NR1H2 (0.41)	NR1H2ESR2NPC1UCHL1RAB9A
SCHEMBL29210587	0.88	DRD2 (0.43)	NR1H2ESR2NPC1DRD2RAB9A
SCHEMBL30983685	0.88	DRD2 (0.43)	NR1H2ESR2NPC1DRD2RAB9A
SCHEMBL30983726	0.85	ESR2 (0.43)	NR1H2ESR2NPC1UCHL1RAB9A
SCHEMBL30983738	0.85	ESR2 (0.43)	NR1H2ESR2NPC1UCHL1RAB9A
SCHEMBL29210621	0.82	DRD2 (0.38)	NPC1DRD2
SCHEMBL30983668	0.79	ESR2 (0.44)	NR1H2ESR2NPC1DRD2RAB9A
SCHEMBL30983724	0.77	ESR2 (0.43)	NR1H2ESR2NPC1UCHL1RAB9A
SCHEMBL29210546	0.77	ESR2 (0.43)	NR1H2ESR2NPC1UCHL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117986264-A	Benzo nitrogen-containing polycyclic derivative regulator and preparation method and application thereof	江苏豪森药业集团有限公司	2024-05-07	—	—	CN	disclosed