Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 9/20 | 0.53 |
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25922621 | 0.92 | UBE2M (0.53) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL7836538 | 0.87 | MAPT (0.52) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26962587 | 0.86 | UBE2M (0.49) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL29858216 | 0.86 | UBE2M (0.49) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL2591241 | 0.85 | ACACB (0.53) | NPC1RAB9AL3MBTL1USP30 | |
| SCHEMBL17141939 | 0.84 | UBE2M (0.62) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL26962484 | 0.82 | MEN1 (0.50) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL8371368 | 0.82 | NPC1 (0.52) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL29858147 | 0.82 | MEN1 (0.50) | UBE2MDCUN1D1LMNATP53MAPT | |
| SCHEMBL23290764 | 0.81 | MAPT (0.43) | UBE2MDCUN1D1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986262-A | Condensed bicyclic compounds, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-05-07 | — | — | CN | disclosed |