SCHEMBL2921143

SCHEMBL2921143

CO[C@H]1CCN(c2cc(C(=O)O)nc(-c3ccccc3)n2)C1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 10/20 0.59
TDP1 Q9NUW8 1/20 0.49
NAPEPLD Q6IQ20 1/20 0.48
USP2 O75604 2/20 0.46
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.46
PKM P14618 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
TTR P02766 2/20 0.44
RBP4 P02753 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521457 1.00 P2RY12 (0.59) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL3059830 1.00 P2RY12 (0.59) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL29521263 0.99 P2RY12 (0.58) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL2928595 0.91 P2RY12 (0.53) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL3044404 0.91 P2RY12 (0.53) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL29510604 0.90 P2RY12 (0.56) P2RY12TDP1NAPEPLDUSP2HPGD
SCHEMBL3051255 0.90 FPR2 (0.52) P2RY12NAPEPLDLMNATTRRBP4
SCHEMBL3051259 0.90 FPR2 (0.52) P2RY12NAPEPLDLMNATTRRBP4
SCHEMBL3062233 0.90 P2RY12 (0.50) P2RY12TDP1NAPEPLDLMNATTR
SCHEMBL3062229 0.90 P2RY12 (0.50) P2RY12TDP1NAPEPLDLMNATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163086-A1 Crystalline Forms VIATRIS ASIA PACIFIC PTE LTD (SG) 2025-05-22 US disclosed
US-12227532-B2 Crystalline forms Viatris Asia Pacific Ptd. Ltd. (SG) 2025-02-18 US disclosed
US-20220275011-A1 CRYSTALLINE FORMS VIATRIS ASIA PACIFIC PTE. LTD. (SG) 2022-09-01 US disclosed
US-11365209-B2 Crystalline forms IDORSIA PHARMACEUTICALS LTD (CH) 2022-06-21 US disclosed
CN-109715639-B Crystalline forms 爱杜西亚药品有限公司 2022-04-19 CN disclosed
EP-3981774-A1 CRYSTALLINE FORMS Idorsia Pharmaceuticals Ltd (CH) 2022-04-13 EP disclosed
EP-3515924-B1 CRYSTALLINE FORMS IDORSIA PHARMACEUTICALS LTD (CH) 2021-12-15 EP disclosed
US-11179390-B2 Subcutaneous administration of a P2Y12 receptor antagonist IDORSIA PHARMACEUTICALS LTD (CH) 2021-11-23 US disclosed
US-20210009614-A1 CRYSTALLINE FORMS IDORSIA PHARMACEUTICALS LTD (CH) 2021-01-14 US disclosed
US-10730896-B2 Crystalline forms IDORSIA PHARMACEUTICALS LTD (CH) 2020-08-04 US disclosed
US-20200129510-A1 SUBCUTANEOUS ADMINISTRATION OF A P2Y12 RECEPTOR ANTAGONIST VIATRIS ASIA PACIFIC PTE. LTD. (SG) 2020-04-30 US disclosed
EP-3595666-A1 SUBCUTANEOUS ADMINISTRATION OF A P2Y12 RECEPTOR ANTAGONIST Idorsia Pharmaceuticals Ltd (CH) 2020-01-22 EP disclosed
EP-3515924-A1 CRYSTALLINE FORMS Idorsia Pharmaceuticals Ltd (CH) 2019-07-31 EP disclosed
WO-2018167139-A1 SUBCUTANEOUS ADMINISTRATION OF A P2Y12 RECEPTOR ANTAGONIST IDORSIA PHARMACEUTICALS LTD (CH) 2018-09-20 WO disclosed
WO-2018055016-A1 CRYSTALLINE FORMS IDORSIA PHARMACEUTICALS LTD (CH) 2018-03-29 WO disclosed
US-8518912-B2 Phosphonic acid derivates and their use as P2Y12 receptor antagonists ACTELION PHARMACEUTICALS LTD. (CH) 2013-08-27 US disclosed
EP-2225253-B1 PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2012-06-27 EP disclosed
US-20100261678-A1 PHOSPHONIC ACID DERIVATES AD THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS VIATRIS ASIA PACIFIC PTE. LTD. (SG) 2010-10-14 US disclosed
EP-2225253-A1 PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS Actelion Pharmaceuticals Ltd. (CH) 2010-09-08 EP disclosed
WO-2009069100-A1 PHOSPHONIC ACID DERIVATES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS ACTELION PHARMACEUTICALS LTD (CH) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261678-A1 PHOSPHONIC ACID DERIVATES AD THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS P2RY12, P2RY13, P2RY11 P2RY12 1/4885TDP1 1192/4885NAPEPLD 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.