D-Glutamate

D-Glutamate

SCHEMBL29211693

CCCCCCCN1C=CN(C)C1.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.46
GRIK2 Q13002 3/20 0.46
SLC1A2 P43004 3/20 0.46
SLC1A1 P43005 3/20 0.46
SLC1A3 P43003 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GSR P00390 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46
GRIA2 P42262 1/20 0.46
GRIA3 P42263 1/20 0.46
GRIA4 P48058 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIK3 Q13003 1/20 0.46
GRIN2B Q13224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL27881574 1.00 GRIK1 (0.46) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
D-Glutamate SCHEMBL28979836 1.00 GRIK1 (0.46) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Glutamic Acid SCHEMBL30335559 1.00 GRIK1 (0.46) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
D-Glutamate SCHEMBL28179361 0.95 SLC1A2 (0.49) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Glutamic Acid SCHEMBL31454133 0.95 SLC1A2 (0.49) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Aspartic Acid SCHEMBL28467895 0.88 GRIK1 (0.44) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Lysine SCHEMBL30335781 0.87 GSR (0.51) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Lysine SCHEMBL28979846 0.87 GSR (0.51) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Lysine SCHEMBL29981026 0.87 GSR (0.51) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
Lysine SCHEMBL27895871 0.87 GSR (0.51) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801032-A Paeoniflorin extraction, separation and purification and anti-aging activity research method thereof 北京石油化工学院 2024-04-02 CN disclosed