Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.71 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184635 | 1.00 | HTR6 (0.71) | HTR6PDK4GRM5GRM1SCN9A | |
| SCHEMBL31155298 | 0.79 | PDK4 (0.63) | HTR6PDK4GRM5GRM1NAMPT | |
| SCHEMBL83151 | 0.79 | PDK4 (0.63) | HTR6PDK4GRM5GRM1NAMPT | |
| SCHEMBL29212411 | 0.79 | HTR6 (0.43) | HTR6DRD2 | |
| SCHEMBL30193218 | 0.76 | PDK4 (0.59) | HTR6PDK4GRM5GRM1SCN9A | |
| SCHEMBL4248631 | 0.76 | PDK4 (0.59) | HTR6PDK4GRM5GRM1SCN9A | |
| SCHEMBL3953658 | 0.74 | PDK4 (0.57) | HTR6PDK4GRM5GRM1NAMPT | |
| SCHEMBL3435107 | 0.74 | PDK4 (0.55) | HTR6PDK4GRM5GRM1NAMPT | |
| SCHEMBL6210879 | 0.74 | HTR6 (0.59) | HTR6PDK4GRM5GRM1SCN9A | |
| SCHEMBL23629157 | 0.73 | PDK4 (0.56) | HTR6PDK4GRM5GRM1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |