Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184533 | 1.00 | AAK1 (0.62) | AAK1GAAMEN1KMT2AS100A4 | |
| SCHEMBL4814398 | 0.79 | AAK1 (0.51) | AAK1GAAMEN1KMT2AIMPDH2 | |
| SCHEMBL4480875 | 0.78 | AAK1 (0.52) | AAK1GAAMEN1KMT2AGABRA1 | |
| SCHEMBL26205134 | 0.77 | S100A4 (0.56) | S100A4TRPV1GABRA1GABRG2GABRB3 | |
| SCHEMBL16454736 | 0.77 | AAK1 (1.00) | AAK1GAAMEN1KMT2AIMPDH2 | |
| SCHEMBL6170216 | 0.73 | AAK1 (0.55) | AAK1GAAMEN1KMT2AS100A4 | |
| SCHEMBL16238827 | 0.73 | AAK1 (0.55) | AAK1GAAMEN1KMT2AS100A4 | |
| SCHEMBL6367662 | 0.73 | AAK1 (0.51) | AAK1IMPDH2MAPTALDH1A1LMNA | |
| SCHEMBL14247302 | 0.73 | AAK1 (0.57) | AAK1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL25033577 | 0.73 | GAA (0.53) | AAK1GAAMEN1KMT2AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813295-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2024-04-02 | — | — | CN | disclosed |