SCHEMBL29212751

SCHEMBL29212751

COc1ccc(Cc2ccccc2)c(OC)c1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CYP2C9 P11712 1/20 0.46
HIF1A Q16665 1/20 0.46
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
ELANE P08246 1/20 0.43
HPGD P15428 1/20 0.43
PPARA Q07869 1/20 0.43
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30826293 0.88 MEN1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL28318659 0.80 SMN1; SMN2 (0.64) POLBSMN1; SMN2KDM4ETAAR1MEN1
SCHEMBL18280539 0.80 CA1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL18280464 0.80 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL4598359 0.79 RXRA (0.56) CA12CA1CA2CA7CA9
SCHEMBL8678225 0.78 PPARA (0.51) CA12CA1CA2CA7CA9
SCHEMBL4849364 0.76 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL28774063 0.76 PPARA (0.59) CA12CA1CA2CA7CA9
SCHEMBL28217561 0.74 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL10597970 0.74 RXRA (0.54) CA9CYP2C9SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117752736-A Traditional Chinese medicine composition for preventing and treating bordetella gallinarum as well as preparation method and application thereof 四川农业大学 2024-03-26 CN disclosed