Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | GRN | P28799 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213402 | 1.00 | NSD2 (0.42) | NSD2ALDH1A1KDM4ENQO1KMT2A | |
| SCHEMBL30903311 | 0.84 | MMP1 (0.45) | ALDH1A1GRNSORT1LMNAHDAC6 | |
| SCHEMBL29213464 | 0.84 | MMP1 (0.45) | ALDH1A1GRNSORT1LMNAHDAC6 | |
| SCHEMBL29213460 | 0.84 | MMP1 (0.45) | ALDH1A1GRNSORT1LMNAHDAC6 | |
| SCHEMBL29213397 | 0.82 | NQO1 (0.40) | ALDH1A1KDM4ENQO1KMT2AFNTA | |
| SCHEMBL29213403 | 0.82 | NQO1 (0.40) | ALDH1A1KDM4ENQO1KMT2AFNTA | |
| SCHEMBL29213242 | 0.80 | KMT2A (0.41) | ALDH1A1KDM4ENQO1KMT2AFNTA | |
| SCHEMBL29213441 | 0.80 | ROS1 (0.43) | ALDH1A1KDM4EKMT2AMAPK8MAPK9 | |
| SCHEMBL17612636 | 0.79 | NSD2 (0.48) | NSD2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL29213429 | 0.79 | GRN (0.42) | NQO1KMT2AFNTAFNTBGRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118019533-A | 2-Amino-5, 5-dimethylhexanoic acid derivatives as sortilin modulators for the treatment of central nervous system diseases | 因苏森斯有限公司 | 2024-05-10 | — | — | CN | disclosed |