Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 8/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866471 | 0.85 | L3MBTL1 (0.34) | EIF4EBP1PIK3CDCYP2C9CYP2C19HPGDS | |
| SCHEMBL29559836 | 0.85 | NQO2 (0.39) | KMT2AMAPT | |
| SCHEMBL27319832 | 0.85 | NQO2 (0.39) | KMT2AMAPT | |
| SCHEMBL29559826 | 0.81 | EIF4EBP1 (0.45) | EIF4EBP1 | |
| SCHEMBL29244552 | 0.81 | EIF4EBP1 (0.45) | EIF4EBP1 | |
| SCHEMBL28704856 | 0.80 | EIF4EBP1 (0.41) | EIF4EBP1 | |
| SCHEMBL29661925 | 0.79 | EIF4EBP1 (0.36) | EIF4EBP1 | |
| SCHEMBL22866469 | 0.79 | EIF4EBP1 (0.36) | EIF4EBP1 | |
| SCHEMBL29244708 | 0.77 | ATR (0.40) | EIF4EBP1HPGDS | |
| SCHEMBL30935743 | 0.77 | ATR (0.40) | EIF4EBP1HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239963-A | Compounds as eIF4E inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |