Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.64 |
| ▸ | AANAT | Q16613 | 1/20 | 0.62 |
| ▸ | CTSC | P53634 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769393 | 1.00 | MEN1 (0.68) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL1769390 | 1.00 | MEN1 (0.68) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL13584565 | 0.91 | MAPT (0.62) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL13584561 | 0.91 | MAPT (0.62) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL15208305 | 0.89 | MEN1 (0.62) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL15208303 | 0.89 | MEN1 (0.62) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL1768952 | 0.88 | AANAT (0.65) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL1768953 | 0.88 | AANAT (0.65) | MEN1KMT2AMTNR1AAANATCTSC | |
| SCHEMBL2824991 | 0.85 | TRPV1 (0.64) | KMT2AMAPTLMNATSHRBLM | |
| SCHEMBL19051489 | 0.84 | MEN1 (0.80) | MEN1KMT2AMTNR1AAANATMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042286-B1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | CRAGMONT PHARMACEUTICALS LLC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1042286-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | Wei, Edward T. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033799-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | WEI EDWARD T (US) | 1999-07-08 | — | — | WO | disclosed |