Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 4/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.66 |
| ▸ | ESRRG | P62508 | 5/20 | 0.59 |
| ▸ | ESRRB | O95718 | 2/20 | 0.59 |
| ▸ | TYR | P14679 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19046865 | 0.87 | ESR1 (0.83) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL11002185 | 0.86 | KMT2A (0.74) | SMN1; SMN2NPC1RAB9AESR1ESR2 | |
| SCHEMBL5456918 | 0.86 | HDAC1 (0.52) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL28674915 | 0.83 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL6400277 | 0.82 | MEN1 (0.68) | NPC1RAB9AMAPTESR1ESR2 | |
| SCHEMBL10392942 | 0.81 | KMT2A (0.65) | SMN1; SMN2NPC1RAB9AMAPTESRRG | |
| Ethylene Glycol SCHEMBL21074267 | 0.81 | CA1 (0.48) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL20672153 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL29700012 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL12376587 | 0.80 | MAPT (0.52) | SMN1; SMN2NPC1RAB9AMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |