Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 5/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.66 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.66 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19046865 | 0.92 | ESR1 (0.83) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL28687916 | 0.89 | KMT2A (0.77) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL10949603 | 0.86 | ALDH1A1 (0.68) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL20672153 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL29700012 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL24793774 | 0.83 | TSHR (0.54) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL10950553 | 0.83 | ESR1 (0.70) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL1129589 | 0.83 | ESR1 (1.00) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL6393345 | 0.83 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9AMAPTESR1 | |
| SCHEMBL29215569 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-A | Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen | 株式会社百乐 | 2021-12-10 | — | — | CN | disclosed |
| CN-113646052-A | Reversible thermal discoloration composition, reversible thermal discoloration microcapsule pigment encapsulating the reversible thermal discoloration composition, and writing instrument using the reversible thermal discoloration microcapsule pigment | 百乐墨水株式会社 | 2021-11-12 | — | — | CN | disclosed |