Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241500 | 1.00 | SSTR4 (0.52) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL20275276 | 0.85 | SSTR4 (0.47) | SSTR4NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL16256017 | 0.85 | SSTR4 (0.48) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL16252816 | 0.85 | SSTR4 (0.48) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL19724556 | 0.85 | SSTR4 (0.48) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL30241440 | 0.85 | SSTR4 (0.48) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL16182190 | 0.84 | SSTR4 (0.46) | SSTR4NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL29215870 | 0.81 | SSTR4 (0.45) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 | |
| SCHEMBL9965952 | 0.81 | KMT2A (0.48) | SSTR4NR1H2USP2SMN1; SMN2EPHX1 | |
| SCHEMBL30241587 | 0.81 | SSTR4 (0.45) | SSTR4NR1H2KDM5AUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461338-B | 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof | 小野药品工业株式会社 | 2024-02-20 | — | — | CN | disclosed |