Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241889 | 0.92 | NISCH (0.35) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL28989154 | 0.92 | NISCH (0.35) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL30241883 | 0.81 | NISCH (0.33) | NISCH | |
| SCHEMBL28989149 | 0.81 | NISCH (0.33) | NISCH | |
| SCHEMBL28989143 | 0.81 | NISCH (0.33) | NISCH | |
| SCHEMBL30203031 | 0.79 | ADRA1A (0.38) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL28989140 | 0.79 | ADRA1A (0.38) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL30241878 | 0.78 | NISCH (0.49) | NISCH | |
| SCHEMBL30241880 | 0.78 | NISCH (0.38) | NISCHADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL28989532 | 0.78 | NISCH (0.38) | NISCHADRA1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043326-A | Benzodiazepine derivatives as GABAA γ1 PAM | 豪夫迈·罗氏有限公司 | 2024-05-14 | — | — | CN | disclosed |