⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854890 | 0.71 | — | — | |
| SCHEMBL10567572 | 0.65 | MAPK1 (0.64) | — | |
| SCHEMBL11098685 | 0.62 | ADORA2A (0.45) | — | |
| SCHEMBL2927541 | 0.55 | — | — | |
| SCHEMBL10867541 | 0.54 | TNKS (0.32) | — | |
| Cyanate SCHEMBL11851963 | 0.54 | DPYD (0.35) | — | |
| SCHEMBL4893972 | 0.54 | — | — | |
| SCHEMBL28301854 | 0.54 | — | — | |
| SCHEMBL4866958 | 0.54 | — | — | |
| SCHEMBL8907 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250340542-A1 | THYROID HORMONE RECEPTOR AGONISTS | INVENTISBIO CO LTD (CN) | 2025-11-06 | — | — | US | disclosed |
| US-12391677-B2 | Thyroid hormone receptor agonists | InventisBio Co., Ltd. (CN) | 2025-08-19 | — | — | US | disclosed |
| US-20210355110-A1 | THYROID HORMONE RECEPTOR AGONISTS | InventisBio Co., Ltd. (CN) | 2021-11-18 | — | — | US | disclosed |
| EP-3864013-A1 | THYROID HORMONE RECEPTOR AGONISTS | InventisBio Co., Ltd. (CN) | 2021-08-18 | — | — | EP | disclosed |
| US-RE46024-E1 | Thyroid hormone analogs | HOFFMANN-LA ROCHE INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-7807674-B2 | Thyroid hormone analogs | HOFFMANN-LA ROCHE INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1919878-B1 | PYRIDAZINONE DERIVATIVES AS THYROID HORMONE RECEPTOR AGONISTS | HOFFMANN LA ROCHE (CH) | 2010-09-08 | — | — | EP | disclosed |
| US-20090005383-A1 | THYROID HORMONE ANALOGS | HOFFMANN-LA ROCHE INC. | 2009-01-01 | — | — | US | disclosed |
| US-7452882-B2 | Thyroid hormone analogs | HOFFMANN-LA ROCHE INC. (US) | 2008-11-18 | — | — | US | disclosed |
| EP-1919878-A1 | PYRIDAZINONE DERIVATIVES AS THYROID HORMONE RECEPTOR AGONISTS | F. Hoffmann-Roche AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| US-20070032494-A1 | Thyroid hormone analogs | HOFFMANN-LA ROCHE INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2007009913-A1 | PYRIDAZINONE DERIVATIVES AS THYROID HORMONE RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-25 | — | — | WO | disclosed |
| US-5464837-A | Antiprotozoa agents and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-07 | — | — | US | disclosed |
| US-5256631-A | Substituted 1,2,4-triazinediones, and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5070091-A | HONEY BEES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4968795-A | PARASITICIDES, ANTIPROTOZOA AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4935423-A | Antiprotozoa agent | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-19 | — | — | US | disclosed |