Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625882 | 0.99 | MAOA (0.54) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL23085369 | 0.92 | MAOA (0.63) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL23085275 | 0.91 | MAOA (0.60) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL31021593 | 0.89 | TDP1 (0.54) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL26840517 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL28051430 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL26840523 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL13592519 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL14103937 | 0.89 | TDP1 (0.67) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL16569093 | 0.88 | TDP1 (0.53) | MAOAMAOBTDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794946-A | Long acting dual GIP/GLP-1 peptide conjugates and methods of use | 斯克利普斯研究所 | 2024-03-29 | — | — | CN | disclosed |