SCHEMBL29216481

SCHEMBL29216481

CCN(C(=O)C(F)F)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
GLA P06280 1/20 0.69
TSHR P16473 1/20 0.69
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
TP53 P04637 2/20 0.50
HTT P42858 1/20 0.46
HPGD P15428 2/20 0.45
MLYCD O95822 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18765958 0.83 ALDH1A1 (0.66) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL263716 0.82 ALDH1A1 (1.00) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL11897377 0.81 ALDH1A1 (0.63) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL28389819 0.81 ALDH1A1 (0.63) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL4055696 0.80 ALDH1A1 (0.61) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL7497334 0.80 ALDH1A1 (0.61) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL11618038 0.80 ALDH1A1 (0.61) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL3838077 0.80 ALDH1A1 (0.61) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL10951512 0.80 ALDH1A1 (0.61) ALDH1A1GLATSHRMEN1KMT2A
SCHEMBL9223060 0.79 ALDH1A1 (0.59) ALDH1A1GLATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 CN claimed
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 CN disclosed