Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 8/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626605 | 0.83 | MAPT (0.37) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL29126349 | 0.83 | MAPT (0.37) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL24716663 | 0.80 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL22500864 | 0.79 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL24715896 | 0.79 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL24716066 | 0.79 | MAPT (0.48) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 | |
| SCHEMBL22501504 | 0.79 | KMT2A (0.60) | MEN1KMT2ASMN1; SMN2CTSBPIN1 | |
| SCHEMBL25248042 | 0.77 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2CTSBPIN1 | |
| SCHEMBL24715852 | 0.77 | SLC6A3 (0.35) | ALDH1A1KDM4EIDO1HSP90AA1CASP6 | |
| SCHEMBL29217777 | 0.76 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2CTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120035438-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-118059101-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2024-05-24 | — | — | CN | disclosed |