Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687025 | 0.82 | HSD17B10 (0.64) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL4687023 | 0.82 | HSD17B10 (0.64) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL4687017 | 0.82 | HSD17B10 (0.64) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL1975200 | 0.81 | MAPT (0.63) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL14482921 | 0.81 | MAPT (0.63) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL1975201 | 0.81 | MAPT (0.63) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL10874198 | 0.81 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL29217646 | 0.81 | MAPT (0.59) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL10874192 | 0.81 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL10004256 | 0.80 | MEN1 (0.55) | MEN1KMT2ARAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756785-A | Preparation and application of N- (pyridine-2-yl) benzo [ b ] five-membered heterocycle-3-carboxamide structure compound | 江西中医药大学 | 2024-03-26 | — | — | CN | disclosed |