Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | APP | P05067 | 9/20 | 0.64 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30884120 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL796265 | 0.88 | MAPT (0.74) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL30504076 | 0.84 | SMN1; SMN2 (1.00) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL2247388 | 0.84 | SMN1; SMN2 (1.00) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4801119 | 0.83 | SULT1A1 (0.84) | MAPTSMN1; SMN2TP53APPSULT1A1 | |
| SCHEMBL10032139 | 0.83 | APP (0.63) | APPSULT1A1GLAGAA | |
| SCHEMBL5429982 | 0.83 | APP (0.83) | KDM4ESMN1; SMN2NPC1APPSULT1A1 | |
| SCHEMBL1987724 | 0.82 | APP (0.72) | APPSULT1A1GLAGAA | |
| SCHEMBL26017584 | 0.79 | APP (0.76) | APPSULT1A1GLAGAA | |
| SCHEMBL5421230 | 0.79 | SMN1; SMN2 (0.78) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756742-A | Benzothiazole compound or salt thereof, preparation method and application thereof | 徐州医科大学 | 2024-03-26 | — | — | CN | disclosed |