Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30162968 | 1.00 | RXRA (0.33) | RXRARXRBRXRGCYP1A2HPGD | |
| SCHEMBL30162928 | 0.88 | RXRA (0.35) | RXRARXRBRXRGMCHR1KDM4C | |
| SCHEMBL30162958 | 0.87 | RXRA (0.32) | RXRARXRBRXRGCYP1A2HPGD | |
| SCHEMBL29218300 | 0.87 | RXRA (0.32) | RXRARXRBRXRGCYP1A2HPGD | |
| SCHEMBL31216565 | 0.86 | KDM4C (0.36) | RXRARXRBRXRGMCHR1KDM4C | |
| SCHEMBL30163054 | 0.83 | HPGD (0.35) | RXRARXRBRXRGCYP1A2HPGD | |
| SCHEMBL29218210 | 0.83 | HPGD (0.35) | RXRARXRBRXRGCYP1A2HPGD | |
| SCHEMBL30163046 | 0.82 | RXRA (0.34) | RXRARXRBRXRGMCHR1KDM4C | |
| SCHEMBL30163167 | 0.81 | RXRA (0.33) | RXRARXRBRXRGMCHR1KDM4C | |
| SCHEMBL24934015 | 0.81 | BRD4 (0.34) | RXRARXRBRXRGHPGDKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118055926-A | ROCK2 inhibitors and uses thereof | 哈佛大学的校长及成员们 | 2024-05-17 | — | — | CN | disclosed |