SCHEMBL29218367

SCHEMBL29218367

Nc1ccc(OCCOc2cccc(N)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
CYP3A4 P08684 2/20 0.60
TP53 P04637 1/20 0.60
MAOB P27338 4/20 0.55
LTA4H P09960 1/20 0.53
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
APP P05067 3/20 0.50
ALDH1A1 P00352 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
MAOA P21397 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31286544 1.00 TSHR (0.61) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL30086150 0.94 TSHR (0.56) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL19935585 0.94 TSHR (0.64) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL19935584 0.92 TSHR (0.72) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL29502076 0.92 CYP3A4 (0.69) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL3791936 0.92 CYP3A4 (0.69) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL7739637 0.90 MAOB (0.67) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL21694001 0.88 CYP3A4 (0.60) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL9064380 0.86 TSHR (0.62) TSHRCYP3A4TP53MAOBLTA4H
SCHEMBL6756802 0.85 TSHR (0.72) TSHRCYP3A4TP53MAOBLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118056157-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-17 CN disclosed
CN-118020020-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-10 CN disclosed
CN-117897656-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-04-16 CN disclosed