Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502076 | 0.94 | CYP3A4 (0.69) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL3791936 | 0.94 | CYP3A4 (0.69) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL3979591 | 0.92 | TSHR (0.74) | MAOBTSHRCYP3A4TP53KCNA3 | |
| SCHEMBL29218367 | 0.90 | TSHR (0.61) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL31286544 | 0.90 | TSHR (0.61) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL9064380 | 0.88 | TSHR (0.62) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL29437009 | 0.87 | TSHR (0.79) | MAOBTSHRCYP3A4TP53KCNA3 | |
| SCHEMBL6756802 | 0.87 | TSHR (0.72) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL29437038 | 0.87 | TSHR (0.72) | MAOBTSHRCYP3A4TP53ALDH1A1 | |
| SCHEMBL441825 | 0.87 | TSHR (0.79) | MAOBTSHRCYP3A4TP53KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420403-B1 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, TRANSPLANT REJECTION AND AUTOIMMUNE DISEASES. | BRISTOL-MYERS SQUIBB COMPANY | 2002-07-16 | — | — | US | disclosed |