Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218845 | 0.85 | SPHK1 (0.50) | SPHK1SMN1; SMN2OPRL1 | |
| SCHEMBL29218752 | 0.84 | SPHK1 (0.56) | SPHK1KDM4ETHRBSLC6A2SLC6A4 | |
| SCHEMBL29218703 | 0.82 | SPHK1 (0.42) | SPHK1RAB9AOPRL1 | |
| SCHEMBL29218804 | 0.79 | OPRL1 (0.39) | SPHK1OPRL1 | |
| SCHEMBL29218865 | 0.75 | KMT2A (0.47) | RAB9AMEN1KMT2A | |
| SCHEMBL25041898 | 0.75 | SPHK1 (0.46) | SPHK1RAB9ASMN1; SMN2KDM4ETHRB | |
| SCHEMBL25041749 | 0.75 | SPHK1 (0.46) | SPHK1RAB9ASMN1; SMN2KDM4ETHRB | |
| SCHEMBL29218802 | 0.75 | OPRL1 (0.32) | OPRL1 | |
| SCHEMBL29218617 | 0.72 | TSHR (0.47) | MEN1KMT2AKDM4E | |
| SCHEMBL11404682 | 0.70 | MAOB (0.50) | RAB9ASMN1; SMN2KDM4ETHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |