SCHEMBL29218751

SCHEMBL29218751

NC1CCC(N)(c2ccc3ccccc3c2)CC1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 12/20 0.49
SLC6A3 Q01959 12/20 0.49
KDM1A O60341 5/20 0.46
RCOR1 Q9UKL0 5/20 0.46
SLC6A2 P23975 4/20 0.45
CYP1A1 P04798 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31008989 1.00 SLC6A4 (0.49) SLC6A4SLC6A3KDM1ARCOR1SLC6A2
SCHEMBL25155815 0.85 SLC6A4 (0.53) SLC6A4SLC6A3KDM1ARCOR1SLC6A2
SCHEMBL31360121 0.85 SLC6A4 (0.53) SLC6A4SLC6A3KDM1ARCOR1SLC6A2
SCHEMBL20104738 0.80 SLC6A2 (0.62) SLC6A4SLC6A3SLC6A2
SCHEMBL3229665 0.80 SMYD3 (0.49)
SCHEMBL4711668 0.77 OPRL1 (0.58)
Hydrochloric Acid SCHEMBL27606531 0.76 OPRL1 (0.56) KDM1A
SCHEMBL29218540 0.75 KDM1A (0.45) KDM1A
SCHEMBL31008877 0.74 SLC6A3 (0.44) SLC6A4SLC6A3KDM1ASLC6A2
SCHEMBL31008897 0.74 OPRL1 (0.39) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076581-A Iron death modulators, their preparation and use 维泰瑞隆有限公司 2024-05-24 CN disclosed