Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219432 | 1.00 | KCNH2 (0.49) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL29219484 | 1.00 | KCNH2 (0.49) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL29219388 | 1.00 | KCNH2 (0.49) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL7039076 | 0.98 | KDM4E (0.49) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL7852029 | 0.94 | MEN1 (0.51) | KDM4ETLR8LMNATSHRMEN1 | |
| SCHEMBL14128989 | 0.87 | KDM4E (0.60) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL20855335 | 0.83 | TLR8 (0.51) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL2126335 | 0.82 | KDM4E (0.54) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL16433240 | 0.82 | KDM4E (0.54) | KCNH2KDM4ETLR8LMNATSHR | |
| SCHEMBL170164 | 0.82 | KDM4E (0.54) | KCNH2KDM4ETLR8LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | disclosed |