Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219632 | 1.00 | POLB (0.57) | POLBHPGDGFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL12444223 | 0.80 | POLB (0.62) | POLBHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10047317 | 0.80 | POLB (0.62) | POLBHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1933183 | 0.78 | ALDH1A1 (0.67) | POLBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3104931 | 0.78 | ALDH1A1 (0.67) | POLBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL1933186 | 0.78 | ALDH1A1 (0.67) | POLBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL1933496 | 0.75 | ALDH1A1 (0.69) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL1933497 | 0.75 | ALDH1A1 (0.69) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL20546289 | 0.73 | HPGD (0.50) | POLBHPGDGFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL20546294 | 0.73 | HPGD (0.50) | POLBHPGDGFERSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |