Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886326 | 0.96 | FFAR1 (0.54) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL10077712 | 0.89 | FFAR1 (0.47) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL10077721 | 0.87 | FFAR1 (0.52) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL10077723 | 0.87 | FFAR1 (0.49) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL2934482 | 0.87 | FFAR1 (0.49) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL222460 | 0.84 | FFAR1 (0.63) | FFAR1 | |
| SCHEMBL2912655 | 0.83 | FFAR1 (0.54) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL10078216 | 0.81 | FFAR1 (0.51) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL225321 | 0.80 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL10077142 | 0.80 | FFAR1 (0.50) | FFAR1FFAR4POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |