Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912655 | 0.91 | FFAR1 (0.54) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL2920491 | 0.85 | KDM4E (0.54) | FFAR1FFAR4L3MBTL1PPARGFAAH | |
| SCHEMBL10064688 | 0.85 | FFAR1 (0.46) | FFAR1FFAR4PPARGALDH1A1TSHR | |
| SCHEMBL10076910 | 0.83 | PPARA (0.55) | FFAR1FFAR4PPARGPPARAPPARD | |
| SCHEMBL10078102 | 0.83 | PPARA (0.60) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL226097 | 0.82 | FFAR1 (0.68) | FFAR1 | |
| SCHEMBL10077235 | 0.81 | FFAR1 (0.48) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL2925885 | 0.81 | FFAR1 (0.53) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL2892878 | 0.80 | FFAR1 (0.48) | FFAR1FFAR4POLBTDP1L3MBTL1 | |
| SCHEMBL2921997 | 0.80 | FFAR1 (0.53) | FFAR1FFAR4POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |