Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220169 | 0.89 | TSHR (0.53) | TSHRHPGDHCAR2ALDH1A1MAPK1 | |
| SCHEMBL2203251 | 0.83 | ALDH1A1 (0.42) | TSHRHPGDHCAR2ALDH1A1LMNA | |
| SCHEMBL16504446 | 0.79 | TSHR (0.41) | TSHRHPGDHCAR2ALDH1A1LMNA | |
| SCHEMBL29220157 | 0.78 | TSHR (0.55) | TSHRHPGDALDH1A1LMNATDP1 | |
| SCHEMBL6062574 | 0.76 | HCAR2 (0.40) | TSHRHCAR2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19552359 | 0.75 | TSHR (0.45) | TSHRHPGDHCAR2ALDH1A1LMNA | |
| SCHEMBL11860438 | 0.74 | ALDH1A1 (0.43) | TSHRHPGDALDH1A1LMNAMAPT | |
| SCHEMBL11865103 | 0.74 | SMN1; SMN2 (0.50) | TSHRHCAR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28303366 | 0.73 | TSHR (0.39) | TSHRHPGDHCAR2ALDH1A1LMNA | |
| SCHEMBL19105389 | 0.72 | HCAR2 (0.38) | TSHRHCAR2ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108878-A | Organic polymer carrier and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-118108878-A | Organic polymer carrier and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-05-31 | — | — | CN | disclosed |