Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCND2 | P30279 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220526 | 0.96 | POLB (0.51) | POLBPTPN11LMNATHRBGPR119 | |
| Hydrochloric Acid SCHEMBL29220508 | 0.85 | KHK (0.45) | LMNAMEN1KMT2ASYKCSF1R | |
| Hydrochloric Acid SCHEMBL30864152 | 0.85 | KHK (0.45) | LMNAMEN1KMT2ASYKCSF1R | |
| SCHEMBL23575650 | 0.84 | CSF1R (0.57) | PTPN11SYKCSF1RCCND3 | |
| SCHEMBL23575656 | 0.81 | MAPT (0.60) | LMNATP53MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30864146 | 0.79 | MELK (0.46) | LMNAMEN1KMT2ASYKCSF1R | |
| Hydrochloric Acid SCHEMBL29220522 | 0.79 | MELK (0.46) | LMNAMEN1KMT2ASYKCSF1R | |
| SCHEMBL23575564 | 0.78 | CSF1R (0.54) | PTPN11SYKCSF1R | |
| SCHEMBL23575543 | 0.77 | NUDT1 (0.46) | LMNATP53MEN1KMT2ACSF1R | |
| SCHEMBL23575854 | 0.75 | MAPT (0.59) | LMNATP53MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117771374-A | Application of NUDT1 in preparing medicine for treating MYC high expression or MYC amplified tumor | 武汉大学 | 2024-03-29 | — | — | CN | disclosed |